Acetonitrile (ACN, CAS No. 75-05-8) is one of the most widely used organic solvents in high-performance liquid chromatography (HPLC). As a professional manufacturer and supplier of acetonitrile, Tianjin Gnee Biotech Co., Ltd. provides high-purity HPLC grade ACN designed to meet the strict requirements of analytical laboratories, pharmaceutical manufacturers, and research institutions.
Uses of Acetonitrile in HPLC
Mobile Phase Solvent in Reversed-Phase HPLC
The primary use of acetonitrile in HPLC is as a mobile phase solvent, especially in reversed-phase chromatography.
Pharmaceutical and API Analysis
HPLC grade acetonitrile is extensively used in pharmaceutical laboratories for:
- Assay determination of active pharmaceutical ingredients (APIs)
- Impurity profiling and stability testing
- Dissolution and formulation analysis
Bioanalytical Sample Preparation
In bioanalytical applications, acetonitrile is commonly used for:
- Protein precipitation from plasma or serum
- Extraction of drugs and metabolites
- Sample cleanup prior to HPLC analysis
Food and Environmental Testing
Acetonitrile plays a key role in analytical methods for:
- Pesticide residue analysis
- Food additive and contaminant testing
- Environmental monitoring of organic pollutants


Why Choose Gneebio as Your Supplier?
As a Acetonitrile (CAS 75-05-8) manufacturer, Gneebio focuses on product consistency, industrial applicability, and bulk supply reliability. The company operates under strict quality management systems to ensure that Acetonitrile (CAS 75-05-8) meets the requirements of large-scale and continuous production environments.
Key manufacturing and supply strengths include:
- Controlled purity grades suitable for industrial and synthetic applications
- Stable batch-to-batch quality for long-term procurement
- Bulk supply capability to support contract and spot orders
- Export-ready packaging and documentation (COA, SDS, etc.)
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