White Powder Dithiothreitol CAS 3483-12-3 For Pharmaceutical
CAS NO.:3483-12-3
EINECS :222-468-7
Formula :C4h1002s2
Classification :Organic Analytical Reagents
Appearance : Powder
Quality : Industrial
Tianjin Gnee Biotech Co., Ltd. is one of the leading manufacturers and suppliers of white powder dithiothreitol cas 3483-12-3 for pharmaceutical in China. Welcome to buy cheap chemical products for sale here from our factory. For price consultation, contact us.
Products Description
Dithiothreitol (DTT), with the chemical formula C₄H₁₀O₂S₂, is a highly potent reducing agent. It exists as a white, crystalline powder at room temperature. It has a melting point in the range of 42 - 43 °C. Under normal conditions, DTT is relatively stable, but it is sensitive to oxidation, so proper storage in an air - tight container away from oxidizing agents is crucial to maintain its reducing activity.
Application
- Dithiothreitol is extensively used in protein research. During protein purification processes, DTT helps prevent the formation of incorrect disulfide bonds, ensuring that proteins fold correctly. It is also used to reduce existing disulfide bonds in proteins, which can be beneficial for studying protein structure and function. In DNA sequencing reactions, DTT is added to the reaction buffer to keep enzymes, such as polymerases, in an active state by protecting their thiol - containing active sites from oxidation.
- In the pharmaceutical industry, DTT finds applications in drug development. It can be used to modify the structure of certain drug molecules by reducing disulfide bonds, which may enhance drug solubility, stability, or bioactivity.
- in cell culture media, DTT is sometimes included to create a reducing environment that promotes cell growth and survival, especially for cells that are sensitive to oxidative stress.
Basic Information
| Product Name: | Dithiothreitol |
| CAS: | 3483-12-3 |
| MF: | C4H10O2S2 |
| MW: | 154.25 |
| EINECS: | 222-468-7 |
| Melting point | 41-44 °C(lit.) |
| alpha | -0.2~+0.2°(20ºC/D)(c=5,H2O) |
| Boiling point | 125 °C |
| density | 1.04 g/mL at 20 °C |
| vapor density | 5.3 (vs air) |
| vapor pressure | 0.019-0.29Pa at 20-50ºC |
| refractive index | 1.5200 (estimate) |
| Fp | >230 °F |
| storage temp. | -20°C (or 4°C short term). |
| solubility | H2O: 50 mg/mL, clear, colorless |
| pka | pK1:8.9 (25°C) |
| form | Powder |
| color | White |
| Odor | Unpleasant Odor |
| PH | 4.0-6.0 (20-25ºC, 0.1m in H2O) |
| PH Range | 4 - 6 at 15,4 g/l at 25 °C |
| Water Solubility | freely soluble |
| λmax | λ: 260 nm Amax: 0.400 λ: 280 nm Amax: 0.100 |
| Sensitive | Air Sensitive |
| Stability: | Stability Stable, but heat sensitive. Incompatible with strong oxidizing agents. Keep frozen at -20 to -10 C. |
Company Profile
Gneebio is a professional chemical raw material manufacturer and global distributor. Our company is located in Henan Province, China. We have multiple partner chemical factories in Henan, covering an area of 3,600 square meters, providing customers with a one-stop chemical procurement service, including mixing, repackaging, storage, and distribution.
Our popular products include Organic Chemicals (Polybutadiene Rubber, Propylene Glycol, Cyclohexanone, Cyclohexane, Paraformaldehyde, Methyl Isobutyl Ketone), Featured Chemicals (Sodium Cocoyl Glutamate, Piperazine Anhydrous, Ethanol Diisopropanolamine, Propyl Gallate), and various Petrochemicals (Ethylene Tar, HP500N, Petroleum Toluene), among others.
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FAQ
Q: Do you provide free samples of galvanized steel metal sheets?
A: Yes, we can provide free samples for testing, and the buyer should bear all shipping costs.
Q: Do you accept small orders?
A: You don't have to worry about this issue, just ask for advice.
Q: Do you accept third-party inspection?
A: Yes, we absolutely accept it.
Q: How about our price?
A: Our prices are very competitive because we are a factory.
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