Is Dimethylacetamide (DMAC) soluble in water?
Dimethylacetamide (DMAC) is a highly polar, aprotic solvent that can dissolve a wide variety of compounds. It is completely miscible with water, acids, bases, and alcohols, and features high thermal stability, low hydrolysis, low corrosivity, and low toxicity. DMAC shows excellent solubility for many resins, especially polyurethane and polyacrylate resins, making it suitable for synthetic fibers, plastic films, coatings, pharmaceuticals, and spandex fiber spinning. As a low-toxicity, high-boiling, highly polar aprotic solvent and chemical intermediate, DMAC has wide applications in synthetic materials, pharmaceuticals, agriculture, chemicals, petrochemicals, and pigments.
Solubility and Physical Data
| Property | Specification |
|---|---|
| Chemical Name | N,N-Dimethylacetamide (DMAC) |
| Molecular Formula | C₄H₉NO |
| Appearance | Colorless, transparent liquid |
| Boiling Point | 165–166°C |
| Density (25°C) | 0.936 g/cm³ |
| Water Solubility | Fully miscible |
| Polarity | Strong polar aprotic solvent |
| Flash Point | 65°C |
| Purity (Industrial Grade) | ≥99% |
Compatibility with Common Industrial Solvents
| Solvent Type | Compatibility with DMAC | Typical Application |
|---|---|---|
| Water | Fully miscible | Cleaning, extraction |
| Methanol | Excellent | Pharmaceutical synthesis |
| Ethanol | Excellent | Polymer processing |
| Acetone | Excellent | Coatings, adhesives |
| Toluene | Partial | Mixed solvent systems |
| Hexane | Poor | Non-polar separation processes |
DMAC Solvent Has Excellent Solubility Performance
DMAC has excellent solubility for a variety of organic and inorganic substances. It can dissolve water, acids, bases, alcohols, and aromatic compounds. It can dissolve unsaturated fats, waxes, and antioxidants, as well as resins such as epoxy resins, vinyl resins, fiber derivatives, phenolic resins, and linear polyester resins.
What are the properties of DMAC solvent?
- Properties:
DMAC is a colorless, transparent liquid that is miscible with water, alcohols, and amines. It is a highly polar solvent with good thermal stability.
- Stability:
DMAC remains stable even at its boiling point and can be purified by distillation. It is stable in aqueous solutions but may hydrolyze in the presence of acids or bases.
- Comparison with DMF:
DMAC contains a methyl group, giving it a higher boiling point than DMF (153°C). This results in better thermal and chemical stability.
- Applications in Synthesis:
DMAC acts as an excellent catalyst, accelerating reactions such as polymerization, carbonylation, oxidation, and deamination, while improving the yield of main products.
Why Purchase Dimethylacetamide (DMAC) From Gneebio?
Gneebio is a trusted manufacturer and supplier with over a decade of experience in the chemical industry. Our Dimethylacetamide is produced under strict ISO and GMP quality systems, ensuring high purity concentration in industrial applications. We offer:
- Product specifications (technical data sheet);
- COA and MSDS;
