What is dimethylformamide DMF (CAS:68-12-2)?
N,N-Dimethylformamide (CAS:68-12-2), with the chemical formula C₃H₇NO, is a colorless, transparent liquid. DMF exhibits strong polarity and is miscible with water, ethers, alcohols, esters, ketones, unsaturated hydrocarbons, and aromatic hydrocarbons. It finds extensive applications in industries such as film manufacturing, fiber production, coatings, pharmaceuticals, synthetic leather, and apparel.
How toxic is N,N-Dimethylformamide (CAS:68-12-2)?
- The toxic effects of N,N-Dimethylformamide (CAS:68-12-2) involve multiple organ systems.
- During acute exposure, its volatile vapors irritate the eyes, skin, and respiratory tract, causing conjunctivitis, dermatitis, and throat discomfort. High-concentration exposure may lead to central nervous system depression, manifesting as dizziness, drowsiness, or even confusion.
- Chronic toxicity is more severe: prolonged exposure can damage the liver (e.g., elevated liver enzymes, fatty degeneration), disrupt the digestive system (nausea, abdominal pain), and potentially affect reproductive health (decreased sperm quality in males).
- Additionally, DMF metabolites may cross the placental barrier, posing risks to fetal development.
What are the safety precautions for using N,N-Dimethylformamide?
- Personal Protection: Wear butyl rubber gloves, impervious aprons, and chemical goggles when handling DMF. For high vapor concentrations, use a Class A organic vapor respirator with cartridges.
- Management Measures: Conduct regular environmental monitoring and employee health examinations (with emphasis on liver function tests). Enhance safety training and strictly prohibit direct skin contact with DMF. For emergency response, immediately wash skin with soap and water if contaminated. Move individuals exposed to inhalation to fresh air and seek medical attention if necessary.
- Storage: Keep away from heat sources and avoid storing DMF with strong oxidizing agents.


Why Choose Gneebio as Your Supplier?
As a N,N-Dimethylformamide (CAS:68-12-2) manufacturer, Gneebio focuses on product consistency, industrial applicability, and bulk supply reliability. The company operates under strict quality management systems to ensure that N,N-Dimethylformamide (CAS:68-12-2) meets the requirements of large-scale and continuous production environments.
Key manufacturing and supply strengths include:
- Controlled purity grades suitable for industrial and synthetic applications
- Stable batch-to-batch quality for long-term procurement
- Bulk supply capability to support contract and spot orders
- Export-ready packaging and documentation (COA, SDS, etc.)





