Triclabendazole, molecular formula C14H9Cl3N2OS, CAS No. 68786-66-3, need to be stored in sealed containers and placed in a cool, dry place, the place of storage must be far away from oxidizing agents, used as a high-efficiency veterinary anthelmintic.
How effective is triclabendazole?
Triclabendazole is the only drug with excellent activities against all stages of the infection. That means that it can be used in the prepatent period, thus preventing the damage caused by adult worms and preventing egg excretion and pasture contamination.
Triclabendazole treatment of sheep, cows, and heifers resulted in a 15.3%, 4.3%, and 36.6% decrease in the proportion of trematode egg counts and production, respectively, suggesting the presence of TCBZ-resistant liver flake trematodes in sheep and cattle on this farm. The action of Triclabendazole sulphoxide (50 mg/mL) on trematodes resulted in extensive disruption of the body wall of Triclabendazole-sensitive liver fluke trematodes, whereas Triclabendazole-resistant trematodes showed only localized and relatively small amounts of disruption of the body wall covering the body spines.
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