N,N-Dimethylacetamide (DMAc) is a colorless, high-boiling, polar aprotic solvent with a boiling point of approximately 165 °C (329–330°F) and a melting/freezing point of approximately -20 °C (-4°F). It is used in various industrial processes, including the production of synthetic fibers, plastics, pharmaceuticals, and electronics.
DMAC is a polar solvent that is miscible with water, alcohols, ethers, and many organic solvents. It has a boiling point of 165–166 °C, making it useful for high-temperature reactions and distillation processes.
N,N-Dimethylacetamide (DMAc) Chemical & Physical Properties
| Item | Property |
|---|---|
| Chemical Name | N,N-Dimethylacetamide |
| Abbreviation | DMAc / DMAC |
| CAS Number | 127-19-5 |
| Molecular Formula | C₄H₉NO |
| Molecular Weight | 87.12 g/mol |
| Appearance | Colorless transparent liquid |
| Odor | Slight amine-like odor |
| Type | Polar aprotic solvent |
Physical Properties
| Item | Value |
|---|---|
| Boiling Point | 165–166°C (329–331°F) |
| Melting/Freezing Point | ~ -20°C (-4°F) |
| Density | ~0.94 g/cm³ (20°C) |
| Refractive Index | ~1.437 |
| Flash Point | ~70–75°C |
| Viscosity | Low |
| Vapor Pressure | Low |
Solubility
| Solvent Type | Solubility Behavior |
|---|---|
| Water | Completely miscible |
| Alcohols | Fully miscible |
| Ethers | Good compatibility |
| Ketones | Fully miscible |
| Most organic solvents | Strong compatibility |
Chemical Properties
| Property | Description |
|---|---|
| Stability | Stable under normal conditions |
| Reactivity | Suitable for various organic reactions |
| Polarity | Medium to strong polar solvent |
| Hydrogen Bonding | Polar aprotic (no hydrogen donation) |
| Thermal Stability | Stable at high temperatures |
| Decomposition | Under strong acids, bases, or extreme heat |
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Applications of N,N-Dimethylacetamide (DMAC)
- Pharmaceutical production: As a solvent for APIs and intermediates.
- Polymer and fiber industry: Dissolving polyacrylonitrile, polyurethane, and polyimides.
- Electronics: Acting as a cleaning agent and reaction solvent in electronic material processing.
- Coatings and adhesives: Providing excellent film-forming and binding capabilities.
Safety Considerations of N,N-Dimethylacetamide (DMAc)
DMAC is classified as a toxic and hazardous substance by various regulatory agencies, including the US Environmental Protection Agency (EPA) and the European Chemicals Agency (ECHA). It can cause skin and eye irritation, respiratory and gastrointestinal effects, and reproductive and developmental toxicity. Prolonged or repeated exposure to DMAC may also cause liver and kidney damage, and increase the risk of cancer.
Therefore, it is important to handle DMAC with appropriate precautions, such as wearing protective clothing, gloves, and goggles, using adequate ventilation and containment systems, and avoiding direct contact and ingestion. DMAC should also be stored and transported in a cool, dry, and well-ventilated area, away from heat sources, ignition sources, and incompatible materials.
Where to Buy N,N-Dimethylacetamide (DMAC)?
When sourcing N,N-Dimethylacetamide (DMAC), choosing a reliable manufacturer is key to ensuring product quality, stable supply, and regulatory compliance. Tianjin Gnee Biotech Co., Ltd. is a professional supplier offering consistent quality and global service.
High Purity & Custom Options
Tianjin Gnee Biotech Co., Ltd. provides high-purity DMAC suitable for industrial, pharmaceutical, and specialty applications, with customizable specifications based on customer needs.
Full Safety Documentation
Complete documents including MSDS, COA, TDS, and shipping papers are available to ensure safe handling and smooth import/export procedures.
Secure Packaging
Professional packaging is used to maintain product stability and prevent moisture contamination during transportation and storage.
International Compliance
The product meets relevant quality and regulatory standards, making it suitable for chemical, pharmaceutical, and electronic industries.
Stable Supply & Global Service
With strong export experience, the company ensures stable supply, competitive pricing, and fast response for both trial and bulk orders.
