Chemical Intermediate Salinomycin CAS 53003-10-4 For Animal Use

Tianjin Gnee Biotech Co., Ltd. is one of the leading manufacturers and suppliers of chemical intermediate salinomycin cas 53003-10-4 for animal use in China. Welcome to buy cheap chemical products for sale here from our factory. For price consultation, contact us.

Salinomycin is a polyether ionic antibiotic isolated from Streptomyces albopictus, which has been successfully used in veterinary medicine as a non steroidal growth promoting and anti coccidian drug for decades.

What is Salinomycin used for?

Animal use field

• Anti coccidiosis effect: Sodium salt mold is a safe and effective anti coccidiosis drug, which is effective against chicken soft and tender Eimeria, toxic Eimeria, giant Eimeria, heap shaped Eimeria, and Ha's Eimeria. It can be used in chicken feed at a dosage of 50-60g/t, but is contraindicated during egg laying period and stopped for 5 days.
• Growth promoting effect: For decades, it has been successfully applied as a non hormonal growth promoting drug in veterinary medicine.

Medical research field

• Anti cancer effect: Salinomycin can kill cancer stem cells in various human cancers by interfering with drug transporter ABC (ATP binding site), Wnt/β - catenin, and other CSC signaling pathways. It can also induce massive apoptosis in human cancer cell lines of different origins.

Mechanism of Action

• Salt mold, as a monovalent cation carrier, has strong selectivity for alkali metal ions, especially for K. It can promote Kefflux from mitochondria and cytoplasm, inhibit oxidative phosphorylation, and play a role in different biofilms (including cell membranes and mitochondrial membranes), exhibiting antibacterial activity against Gram positive bacteria.

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